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Article

A common mechanism for mitotic inactivation of C2H2 zinc finger DNA-binding domains.

Genes & development - 1 Dec 2002

Dovat Sinisa, Ronni Tapani, Russell Dana, Ferrini Roger, Cobb Bradley S, Smale Stephen T

Abstract excerpt

Many nuclear proteins are inactivated during mitotic entry, presumably as a prerequisite to chromatin condensation and cell division. C2H2 zinc fingers define the largest transcription factor family in the human proteome. The linker separating finger motifs is highly conserved and resembles TGEKP...

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Identifiers

PMID: 12464629
DOI: 10.1101/gad.1040502
PMCID: PMC187490

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12464629-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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