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Article

N-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis.

Nature cell biology - 1 May 2007

Chen Ting, Muratore Tara L, Schaner-Tooley Christine E, Shabanowitz Jeffrey, Hunt Donald F, Macara Ian G

Abstract excerpt

Regulator of chromatin condensation 1 (RCC1) is the only known guanine nucleotide-exchange factor for the Ran GTPase and has pivotal roles in nucleo-cytoplasmic transport, mitosis, and nuclear-envelope assembly. RCC1 associates dynamically with chromatin through binding to histones H2A and/or H2B...

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Share to Chromatin Assembly and Disassembly
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17435751
DOI: 10.1038/ncb1572
PMCID: PMC4624279

Genes

RCC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17435751-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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