Article
Bookmarking target genes in mitosis: a shared epigenetic trait of phenotypic transcription factors and oncogenes?
Cancer research - 15 Jan 2014
Zaidi Sayyed K, Grandy Rodrigo A, Lopez-Camacho Cesar, Montecino Martin, van Wijnen Andre J, Lian Jane B, Stein Janet L, Stein Gary S
Abstract excerpt
The regulatory information for phenotype, proliferation, and growth of normal and tumor cells must be maintained through genome replication in the S phase and cell division during mitosis. Epigenetic mechanisms that include DNA methylation, posttranslational modifications of histones, selective utilization of histone variants, and inheritable RNA molecules play pivotal roles in maintaining cellular identity...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
