Article
Serpin peptidase inhibitor (SERPINB5) haplotypes are associated with susceptibility to hepatocellular carcinoma.
Scientific reports - 25 May 2016
Yang Shun-Fa, Yeh Chao-Bin, Chou Ying-Erh, Lee Hsiang-Lin, Liu Yu-Fan
Abstract excerpt
Hepatocellular carcinoma (HCC) represents the second leading cause of cancer-related death worldwide. The serpin peptidase inhibitor SERPINB5 is a tumour-suppressor gene that promotes the development of various cancers in humans. However, whether SERPINB5 gene variants play a role in HCC susceptibility remains unknown. In this study, we genotyped 6 SNPs of the SERPINB5 gene in an independent cohort from a...
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