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Article

Association and functional significance of genetic variants present in regulatory elements of SERPINB5 gene in gallbladder cancer.

Gene - 15 Jan 2022

Sinha Kirti Kumari, Vinay J, Parida Suryakant, Singh Shivaram Prasad, Dixit Manjusha

Abstract excerpt

SERPINB5 is a mammary serine protease inhibitor, which is involved in various cellular functions. The aberrant expression of SERPINB5 is reported in many cancers along with GBC but limited information is available about its role in genetic predisposition for GBC. We carried out case-control study in 206 cases and 219 controls. Promoter SNPs were genotyped by Sanger's sequencing. In-silico promoter analysis and...

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Identifiers

PMID: 34624458
DOI: 10.1016/j.gene.2021.145989

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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