SERBP1 promoter single nucleotide polymorphism (SNP) rs3762314: a genetic susceptibility biomarker promoting malignant phenotype in hepatocellular carcinoma.

doi:10.1016/j.bbrc.2026.154370

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Article

SERBP1 promoter single nucleotide polymorphism (SNP) rs3762314: a genetic susceptibility biomarker promoting malignant phenotype in hepatocellular carcinoma.

Biochemical and biophysical research communications - 24 Sept 2026

Wang Meixia, Liu Han, Guo Cancan, Li Huanteng, Liu Shihai, Wu Xiaopan

Abstract excerpt

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortality worldwide. SERPINE1 mRNA binding protein 1 (SERBP1) has been implicated as an oncogenic factor in HCC; however, the role of SERBP1 single nucleotide polymorphisms (SNPs) in HCC susceptibility and progression remains unclear. This study aimed to identify functional regulatory SNPs in SERBP1 associated with HCC risk and...

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Identifiers

PMID: 42542044
DOI: 10.1016/j.bbrc.2026.154370

Genes

SERBP1
SERPINE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.