Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation in ABCB5 associates with risk of hepatocellular carcinoma.

Journal of cellular and molecular medicine - 1 Sept 2020

Leung Idy C-Y, Chong Charing C-N, Cheung Tan T, Yeung Philip C, Ng Kelvin K-C, Lai Paul B-S, Chan Stephen L, Chan Anthony W-H, Tang Patrick M-K, Cheung Siu T

Abstract excerpt

Expression of ATP-binding cassette B5 (ABCB5) has been demonstrated to confer chemoresistance, enhance cancer stem cell properties and associate with poor prognosis in hepatocellular carcinoma (HCC). The aim of this study was to evaluate the genetic variations of ABCB5 in HCC patients with reference to healthy individuals and the clinicopathological significance. A pilot study has examined 20 out of 300 pairs HCC...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP Binding Cassette Transporter, Subfamily B
Share to Disease-Free Survival

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to INDEL Mutation

Share to Kaplan-Meier Estimate

Share to Pilot Projects

Share to Proportional Hazards Models

Share to RNA, Neoplasm

Share to Vertebrates

Source

Open in PubMed Open full text

Identifiers

PMID: 32783366
DOI: 10.1111/jcmm.15691
PMCID: PMC7521249

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation in ABCB5 associates with risk of hepatocellular carcinoma.PMID 32783366Read ↗

A rare CHD5 haplotype and its interactions with environmental factors predicting hepatocellular carcinoma risk.Semantic proximity Read ↗

Molecular evolutionary analysis of ABCB5: the ancestral gene is a full transporter with potentially deleterious single nucleotide polymorphisms.Semantic proximity Read ↗

Identification of ABCC5 Among ATP-Binding Cassette Transporter Family as a New Biomarker for Hepatocellular Carcinoma Based on Bioinformatics AnalysisSemantic proximity Read ↗

Serpin peptidase inhibitor (SERPINB5) haplotypes are associated with susceptibility to hepatocellular carcinoma.Semantic proximity Read ↗

Polymorphisms of a Disintegrin and Metalloproteinase with Thrombospondin Motifs 5 and Aflatoxin B1-Related Hepatocellular Carcinoma.Semantic proximity Read ↗

Association Between a Variant in ADAMTS5 and the Susceptibility to Hepatocellular Carcinoma in a Chinese Han Population.Semantic proximity Read ↗

Gene-wide characterization of common quantitative trait loci for ABCB1 mRNA expression in normal liver tissues in the Chinese population.Semantic proximity Read ↗

Clinical Significance and Potential Mechanisms of ATP Binding Cassette Subfamily C Genes in Hepatocellular CarcinomaSemantic proximity Read ↗

Association between indel polymorphism in the promoter region of lncRNA GAS5 and the risk of hepatocellular carcinoma.Semantic proximity Read ↗

Deciphering the roles of ABCB5 in normal and cancer cellsSemantic proximity Read ↗

CD44 gene polymorphisms on hepatocellular carcinoma susceptibility and clinicopathologic features.Semantic proximity Read ↗

ABCG5/8 variants are associated with susceptibility to coronary heart disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.