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Article

Assessment of 25 CYP2D6 alleles found in the Chinese population on propafenone metabolism in vitro.

Canadian journal of physiology and pharmacology - 1 Aug 2016

Su Ying, Liang Bing-Qing, Feng Yan-Lin, Zhan Yunyun, Gu Ermin, Chen Xinxin, Dai Da-Peng, Hu Guo-Xin, Cai Jian-Ping

Abstract excerpt

Cytochrome P450 enzyme 2D6 (CYP2D6) is an important member of the cytochrome P450 enzyme superfamily, with more than 100 CYP2D6 allelic variants being previously reported. The aim of this study was to assess the catalytic characteristics of 25 alleles (CYP2D6.1 and 24 CYP2D6 variants) and their effects on the metabolism of propafenone in vitro. Twenty-five CYP2D6 alleles were expressing in 21 Spodoptera...

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Identifiers

PMID: 27203132
DOI: 10.1139/cjpp-2015-0509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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