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Article

The role of Wnt/β-catenin signaling pathway in melanoma epithelial-to-mesenchymal-like switching: evidences from patients-derived cell lines.

Oncotarget - 12 Jul 2016

Kovacs Daniela, Migliano Emilia, Muscardin Luca, Silipo Vitaliano, Catricalà Caterina, Picardo Mauro, Bellei Barbara

Abstract excerpt

Deregulations or mutations of WNT/β-catenin signaling have been associated to both tumour formation and progression. However, contradictory results concerning the role of β-catenin in human melanoma address an open question on its oncogenic nature and prognostic value in this tumour. Changes in WNT signaling pathways have been linked to phenotype switching of melanoma cells between a highly...

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Source

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Identifiers

PMID: 27175588
DOI: 10.18632/oncotarget.9232
PMCID: PMC5190024

Genes

TCF4
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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