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Article

Wnt-beta-catenin pathway signals metastasis-associated tumor cell phenotypes in triple negative breast cancers.

Oncotarget - 12 Jul 2016

De Pradip, Carlson Jennifer H, Wu Hui, Marcus Adam, Leyland-Jones Brian, Dey Nandini

Abstract excerpt

Tumor cells acquire metastasis-associated (MA) phenotypes following genetic alterations in them which cause deregulation of different signaling pathways. Earlier, we reported that an upregulation of the Wnt-beta-catenin pathway (WP) is one of the genetic salient features of triple-negative breast cancer (TNBC), and WP signaling is associated with metastasis in TNBC. Using cBioPortal, here we found that collective...

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Source

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Identifiers

PMID: 27281609
DOI: 10.18632/oncotarget.8988
PMCID: PMC5190013

Genes

MMP7
APC
CTNNB1
DVL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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