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Article

The WNT/Beta-catenin pathway in melanoma

1 Jan 2006

Abstract excerpt

The Wnt/beta-catenin pathway is involved in various cellular activities--including determination, proliferation, migration and differentiation--in embryonic development and adult homeostasis. The deregulation or constitutive activation of the Wnt/beta-catenin pathway may lead to cancer formation. This review focuses on the role of the Wnt/beta-catenin canonical signaling pathway in the melanocyte lineage, and...

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Identifiers

PMID: 16146765
DOI: 10.2741/1831

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