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Article

Development and Preclinical Application of an Immunocompetent Transplant Model of Basal Breast Cancer with Lung, Liver and Brain Metastases.

PloS one - 1 Jan 2016

Aprelikova Olga, Tomlinson Christine C, Hoenerhoff Mark, Hixon Julie A, Durum Scott K, Qiu Ting-Hu, He Siping, Burkett Sandra, Liu Zi-Yao, Swanson Steven M, Green Jeffrey E

Abstract excerpt

Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer that is associated with a poor prognosis and for which no targeted therapies currently exist. In order to improve preclinical testing for TNBC that relies primarily on using human xenografts in immunodeficient mice, we have developed a novel immunocompetent syngeneic murine tumor transplant model for basal-like triple-negative breast...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 27171183
DOI: 10.1371/journal.pone.0155262
PMCID: PMC4865188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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