Article

From Hurdles to Breakthroughs: Building and Validating a PSMA-positive Triple-Negative Breast Cancer Mouse Model for Preclinical Targeted Radionuclide Therapy

2025-11-11

Abstract excerpt

<title>Abstract</title> <p> Background Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, for which targeted therapies are emerging. Prostate-specific membrane antigen (PSMA), expressed mainly by the endothelial cells of the neovascularization of TNBC, or tumor cells, is an interesting target in TNBC that needs to be studied. This study aims to validate a reproductible, PSMA-po...

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Literature Corpus work: 12b3b268-b8b5-5b0a-a300-dd5129561306
DOI: 10.21203/rs.3.rs-7904335/v1

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