Article

EGFR as a potent CAR T target in Triple Negative Breast Cancer Brain Metastases

2022-07-14

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose</bold> There is currently no curative treatment for patients diagnosed with triple-negative breast cancer brain metastases (TNBC-BM). CAR T cells hold potential for curative treatment given they retain the cytolytic activity of a T cell combined with the specificity of an antibody. In this proposal we evaluated the potential of EGFR re-directed CAR T cells as a therapeutic...

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Literature Corpus work: 5b5b45c2-3a2e-5d3b-a443-c06c248d7afc
DOI: 10.21203/rs.3.rs-1828989/v1

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