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Robust and Cost-Effective Pharmacological Immunosuppression Enables Establishment of Nigerian Patient-Derived Xenograft (PDX) Models of Triple-Negative Breast Cancer (TNBC) in Low-Resource Settings

2025-06-24

Abstract excerpt

<title>Abstract</title> <p>Background Genetically immunodeficient mouse models such as NOD/SCID and nude strains are widely used in cancer research for establishing patient-derived xenografts (PDXs). However, these models are expensive, require specialized facilities, and do not adequately reflect human immune-tumour interactions. This study aimed to develop a cost-effective and immunologically relevant pharmaco...

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Literature Corpus work
5838ea4b-36e4-5f45-abe3-e1ac5616a391
DOI
10.21203/rs.3.rs-6913154/v1
Open publication

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Robust and Cost-Effective Pharmacological Immunosuppression Enables Establishment of Nigerian Patient-Derived Xenograft (PDX) Models of Triple-Negative Breast Cancer (TNBC) in Low-Resource SettingsDOI 10.21203/rs.3.rs-6913154/v1
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