Article

Comparing syngeneic and autochthonous models of breast cancer to identify tumor immune components that correlate with response to immunotherapy in breast cancer

2021-01-28

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> The heterogeneity of the breast tumor microenvironment (TME) may contribute to the lack of durable responses to immune checkpoint blockade (ICB), however, mouse models to test this are currently lacking. Proper selection and use of preclinical models are necessary for rigorous, preclinical studies to rapidly move laboratory findings into the clinic to treat pati...

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Literature Corpus work: e24f22d8-9b0c-5fcf-9f63-219a49b10ce5
DOI: 10.21203/rs.3.rs-57679/v2

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