Article
Fine mapping under linkage peaks for symptomatic or asymptomatic outcomes of Leishmania infantum infection in Brazil.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Sept 2016
Weirather Jason L, Duggal Priya, Nascimento Eliana L, Monteiro Gloria R, Martins Daniella R, Lacerda Henio G, Fakiola Michaela, Blackwell Jenefer M, Jeronimo Selma M B, Wilson Mary E
Abstract excerpt
Infection with the protozoan Leishmania infantum can lead to asymptomatic infection and protective immunity, or to the progressive and potentially fatal disease visceral leishmaniasis (VL). Published studies show host genetic background determines in part whether infected individuals will develop a symptomatic or asymptomatic outcome. The purpose of the current study was to fine map chromosome regions previously...
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