Article
A major susceptibility locus for leprosy in India maps to chromosome 10p13.
Nature genetics - 1 Apr 2001
Siddiqui M R, Meisner S, Tosh K, Balakrishnan K, Ghei S, Fisher S E, Golding M, Shanker Narayan N P, Sitaraman T, Sengupta U, Pitchappan R, Hill A V
Abstract excerpt
Leprosy, a chronic infectious disease caused by Mycobacterium leprae, is prevalent in India, where about half of the world's estimated 800,000 cases occur. A role for the genetics of the host in variable susceptibility to leprosy has been indicated by familial clustering, twin studies, complex segregation analyses and human leukocyte antigen (HLA) association studies. We report here a genetic linkage scan of the...
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