A Genome-wide Association Study Identifies SERPINB10, CRLF3, STX7, LAMP3, IFNG-AS1, and KRT80 As Risk Loci Contributing to Cutaneous Leishmaniasis in Brazil.

doi:10.1093/cid/ciaa1230

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A Genome-wide Association Study Identifies SERPINB10, CRLF3, STX7, LAMP3, IFNG-AS1, and KRT80 As Risk Loci Contributing to Cutaneous Leishmaniasis in Brazil.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 18 May 2021

Castellucci Léa C, Almeida Lucas, Cherlin Svetlana, Fakiola Michaela, Francis Richard W, Carvalho Edgar M, Santos da Hora Anadílton, do Lago Tainã Souza, Figueiredo Amanda B, Cavalcanti Clara M, Alves Natalia S, Morais Katia L P, Teixeira-Carvalho Andréa, Dutra Walderez O, Gollob Kenneth J, Cordell Heather J, Blackwell Jenefer M

Abstract excerpt

BACKGROUND: Our goal was to identify genetic risk factors for cutaneous leishmaniasis (CL) caused by Leishmania braziliensis. METHODS: Genotyping 2066 CL cases and 2046 controls using Illumina HumanCoreExomeBeadChips provided data for 4 498 586 imputed single-nucleotide variants (SNVs). A genome-wide association study (GWAS) using linear mixed models took account of genetic diversity/ethnicity/admixture....

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PMID: 32830257
DOI: 10.1093/cid/ciaa1230
PMCID: PMC8130031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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