Article
A fine mapping of single nucleotide variants and haplotype analysis of IL13 gene in patients with Leishmania guyanensis-cutaneous leishmaniasis and plasma cytokines IL-4, IL-5, and IL-13.
Frontiers in immunology - 1 Jan 2023
Junior José do Espírito Santo, de Souza Josué Lacerda, da Silva Lener Santos, da Silva Cilana Chagas, do Nascimento Tuanny Arruda, de Souza Mara Lúcia Gomes, da Cunha Alyne Farias, Batista Jacqueline da Silva, Neto José Pereira de Moura, Guerra Marcus Vinitius de Farias, Ramasawmy Rajendranath
Abstract excerpt
Introduction: Leishmaniasis continues to pose a substantial health burden in 97 countries worldwide. The progression and outcome of Leishmania infection are influenced by various factors, including the cytokine milieu, the skin microbiota at the infection site, the specific Leishmania species involved, the genetic background of the host, and the parasite load. In endemic regions to leishmaniasis, only a fraction...
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