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Article

Comprehensive candidate gene analysis for symptomatic or asymptomatic outcomes of Leishmania infantum infection in Brazil.

Annals of human genetics - 1 Jan 2017

Weirather Jason L, Duggal Priya, Nascimento Eliana L, Monteiro Gloria R, Martins Daniella R, Lacerda Henio G, Fakiola Michaela, Blackwell Jenefer M, Jeronimo Selma M B, Wilson Mary E

Abstract excerpt

Genetic risk factors contribute to asymptomatic versus symptomatic visceral leishmaniasis (VL) outcomes following infection with Leishmania infantum. We therefore carried out a family-based (n = 918 post-quality control fully genotyped and phenotyped individuals) candidate gene study for symptomatic VL or asymptomatic delayed-type hypersensitivity (DTH) skin test phenotypes in highly endemic neighborhoods of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28054334
DOI: 10.1111/ahg.12180
PMCID: PMC5298939

Genes

SMAD7
TGFBR2

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