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Article

ASAFE: ancestry-specific allele frequency estimation.

Bioinformatics (Oxford, England) - 15 Jul 2016

Zhang Qian S, Browning Brian L, Browning Sharon R

Abstract excerpt

UNLABELLED: In a genome-wide association study (GWAS) of an admixed population, such as Hispanic Americans, ancestry-specific allele frequencies can inform the design of a replication GWAS. We derive an EM algorithm to estimate ancestry-specific allele frequencies for a bi-allelic marker given genotypes and local ancestries on a 3-way admixed population, when the phase of each admixed individual's genotype...

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Identifiers

PMID: 27153656
DOI: 10.1093/bioinformatics/btw220
PMCID: PMC4937201

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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