Article
Accurate inference of local phased ancestry of modern admixed populations.
Scientific reports - 23 Jul 2014
Ma Yamin, Zhao Jian, Wong Jian-Syuan, Ma Li, Li Wenzhi, Fu Guoxing, Xu Wei, Zhang Kui, Kittles Rick A, Li Yun, Song Qing
Abstract excerpt
Population stratification is a growing concern in genetic-association studies. Averaged ancestry at the genome level (global ancestry) is insufficient for detecting the population substructures and correcting population stratifications in association studies. Local and phase stratification are needed for human genetic studies, but current technologies cannot be applied on the entire genome data due to various...
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