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Article

Tumor suppressive actions of the nuclear receptor corepressor 1.

Pharmacological research - 1 Jun 2016

Martínez-Iglesias Olaia, Alonso-Merino Elvira, Aranda Ana

Abstract excerpt

Nuclear Receptor Corepressor 1 (NCoR) is an important transcriptional regulator that interacts with nuclear receptors and other transcription factors. Recent results have shown the presence of inactivating mutations or deletions of the NCoR gene in human tumors. NCoR has a strong tumor suppressor activity, inhibiting invasion, metastasis formation and tumor growth in xenograft mouse models. These changes are...

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Identifiers

PMID: 27149915
DOI: 10.1016/j.phrs.2016.04.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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