Article
Oncogenesis of RON receptor tyrosine kinase: a molecular target for malignant epithelial cancers.
Acta pharmacologica Sinica - 1 Jun 2006
Wang Ming-Hai, Yao Hang-Ping, Zhou Yong-Qing
Abstract excerpt
Recepteur d'origine nantais (RON) belongs to a subfamily of receptor tyrosine kinases (RTK) with unique expression patterns and biological activities. RON is activated by a serum-derived growth factor macrophage stimulating protein (MSP). The RON gene transcription is essential for embryonic development and critical in regulating certain physiological processes. Recent studies have indicated that altered RON...
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