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Article

The multifaceted therapeutic value of targeting steroid receptor coactivator-1 in tumorigenesis

29 Mar 2024

Abstract excerpt

Steroid receptor coactivator-1 (SRC-1, also known as NCOA1) frequently functions as a transcriptional coactivator by directly binding to transcription factors and recruiting to the target gene promoters to promote gene transcription by increasing chromatin accessibility and promoting the formation of transcriptional complexes. In recent decades, various biological and pathological functions of SRC-1 have been...

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PMID: 38553750
DOI: 10.1186/s13578-024-01222-8

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