Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Testicular orphan receptor 4 (TR4) is a marker for metastasis and poor prognosis in non-small cell lung cancer that drives the EMT phenotype.

Lung cancer (Amsterdam, Netherlands) - 1 Sept 2015

Zhang Liyi, Zhang Jianzhi, Ma Yuanyuan, Chen Jinfeng, Dong Bin, Zhao Wei, Wang Xing, Zheng Qinfeng, Fang Fang, Yang Yue

Abstract excerpt

OBJECTIVES: Aberrant expression of testicular orphan receptor 4 (TR4) has been shown to regulate biological processes near solid tumors. However, the role of TR4 in non-small cell lung cancer (NSCLC) patient prognosis and the development of NSCLC cancer cells are unclear. METHODS: Immunohistochemical analysis was used to evaluate the correlation between TR4 expression and clinicopathological characteristics in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Non-Small-Cell Lung
Share to Cell Movement

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epithelial-Mesenchymal Transition

Share to Gene Knockdown Techniques

Share to Neoplasm Grading

Share to Neoplasm Metastasis

Share to Neoplasm Staging

Share to Survival Analysis

Source

Identifiers

PMID: 26144287
DOI: 10.1016/j.lungcan.2015.06.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Testicular orphan receptor 4 (TR4) is a marker for metastasis and poor prognosis in non-small cell lung cancer that drives the EMT phenotype.PMID 26144287Read ↗

Testicular orphan receptor 4 promotes tumor progression and implies poor survival through AKT 3 regulation in seminomaSemantic proximity Read ↗

The molecular mechanisms and therapeutic strategies of EMT in tumor progression and metastasisSemantic proximity Read ↗

Crosstalk of Long Non-coding RNAs and EMT: Searching the Missing Pieces of an Incomplete Puzzle for Lung Cancer TherapySemantic proximity Read ↗

Epithelial to Mesenchymal Transition in Lung Cancer: Potential EMT-Targeting Natural Product-derived CompoundsSemantic proximity Read ↗

Testicular Orphan Receptor 4 (TR4) Promotes Papillary Thyroid Cancer Invasion via Activating Circ-FNLA/miR-149-5p/MMP9 SignalingSemantic proximity Read ↗

EMT and tumor metastasisSemantic proximity Read ↗

LncRNA SLCO4A1-AS1 suppresses lung cancer progression by sequestering the TOX4-NTSR1 signaling axisSemantic proximity Read ↗

CNOT4 suppresses nonsmall cell lung cancer progression by promoting the degradation of PAF1Semantic proximity Read ↗

LncRNA PKMYT1AR promotes cancer stem cell maintenance in non-small cell lung cancer via activating Wnt signaling pathwaySemantic proximity Read ↗

Nuclear protein in testis carcinoma of the lungSemantic proximity Read ↗

Nuclear receptor TLX functions to promote cancer stemness and EMT in prostate cancer via its direct transactivation of CD44 and stem cell-regulatory transcription factorsSemantic proximity Read ↗

RYBP Inhibits Progression and Metastasis of Lung Cancer by Suppressing EGFR Signaling and Epithelial-Mesenchymal TransitionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.