Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nuclear Receptor Corepressor 1 Expression and Output Declines with Prostate Cancer Progression

11 Mar 2016

Abstract excerpt

PURPOSE: Castration therapy in advanced prostate cancer eventually fails and leads to the development of castration-resistant prostate cancer (CRPC), which has no cure. Characteristic features of CRPC can be increased androgen receptor (AR) expression and altered transcriptional output. We investigated the expression of nuclear receptor corepressor 1 (NCOR1) in human prostate and prostate cancer and the role of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Estrogen and related hormone effects
Share to Prostate Cancer Treatment and Research
Share to Receptor Mechanisms and Signaling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26968201
DOI: 10.1158/1078-0432.ccr-15-1983

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nuclear Receptor Corepressor 1 Expression and Output Declines with Prostate Cancer ProgressionPMID 26968201Read ↗

Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancerSemantic proximity Read ↗

Development and prevalence of castration-resistant prostate cancer subtypesSemantic proximity Read ↗

Transcriptional repression by androgen receptor: roles in castration-resistant prostate cancerSemantic proximity Read ↗

Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancerSemantic proximity Read ↗

PHENOTYPIC CHARACTERIZATION OF TWO NOVEL CELL LINE MODELS OF CASTRATION RESISTANT PROSTATE CANCERSemantic proximity Read ↗

GREB1 amplifies androgen receptor output in human prostate cancer and contributes to antiandrogen resistanceSemantic proximity Read ↗

Activation of Notch1 synergizes with multiple pathways in promoting castration-resistant prostate cancer.Semantic proximity Read ↗

Phenotypic characterization of two novel cell line models of castration-resistant prostate cancer.Semantic proximity Read ↗

Targeting Androgen Receptor Activation Function-1 with EPI to Overcome Resistance Mechanisms in Castration-Resistant Prostate Cancer.Semantic proximity Read ↗

GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistanceSemantic proximity Read ↗

Identification of AR-V7 downstream genes commonly targeted by AR/AR-V7 and specifically targeted by AR-V7 in castration resistant prostate cancerSemantic proximity Read ↗

Corepressive function of nuclear receptor coactivator 2 in androgen receptor of prostate cancer cells treated with antiandrogen.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.