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Article

Testing the Activity of Complement Convertases in Serum/Plasma for Diagnosis of C4NeF-Mediated C3 Glomerulonephritis.

Journal of clinical immunology - 1 Jul 2016

Blom Anna M, Corvillo Fernando, Magda Michal, Stasiłojć Grzegorz, Nozal Pilar, Pérez-Valdivia Miguel Ángel, Cabello-Chaves Virginia, Rodríguez de Córdoba Santiago, López-Trascasa Margarita, Okrój Marcin

Abstract excerpt

Autoantibodies termed C3-nephritic factor (C3NeF), which stabilize convertases of the alternative complement pathway, often stimulate autoinflammatory diseases. However, knowledge about analogous autoantibodies acting on the classical pathway (C4NeF) is limited to a few reports, which indicate association with kidney dysfunction, systemic lupus erythematous, and infections. C4NeF may appear independently from...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27146825
DOI: 10.1007/s10875-016-0290-5
PMCID: PMC4896984

Genes

CFB
CFH
CFI
DGKE
THBD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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