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Article

C3 Glomerulopathy: A Current Perspective in an Evolving Landscape

30 Oct 2024

Abstract excerpt

Background: Complement 3 (C3) glomerulopathy (C3G) is a heterogenous disease characterized by dysregulation of the complement alternative pathway. Within 10 years of a diagnosis, roughly 50% of patients with C3G will progress to end-stage kidney disease. Historically, treatment options have been limited to nonspecific immune suppression with suboptimal response rates to recommended therapies. Advances in...

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Share to Coagulation, Bradykinin, Polyphosphates, and Angioedema
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PMID: 39618492
DOI: 10.1159/000542354

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