Article
Case report: lupus nephritis with autoantibodies to complement alternative pathway proteins and C3 gene mutation.
BMC nephrology - 30 Mar 2015
Nozal Pilar, Garrido Sofía, Martínez-Ara Jorge, Picazo María Luz, Yébenes Laura, Álvarez-Doforno Rita, Pinto Sheila, de Córdoba Santiago Rodríguez, López-Trascasa Margarita
Abstract excerpt
BACKGROUND: Glomerulonephritis is one of the most severe complications of lupus, a systemic disease with multi-organ involvement, with tissue damage produced mainly by complement activation. As a result of this activation, patients with active lupus present hypocomplementemia during disease flares, but C3 and C4 levels are recovered between episodes. CASE PRESENTATION: We present a patient who suffered two lupus...
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