Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

C3 glomerulopathy: a kidney disease mediated by alternative pathway deregulation

29 Oct 2024

Abstract excerpt

C3 glomerulopathy (C3G) is an ultra-rare complement-mediated kidney disease caused by to the deregulation of the alternative pathway (AP) of proximal complement. Consequently, all effector loops of the complement are active and can lead to pathologies, such as C3a- and C5a-mediated inflammation, C3b opsonization, surface C3b-mediated AP C3 convertase assembly, C3 cleavage product deposition in the glomerulus, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood groups and transfusion
Share to Complement system in diseases
Share to Renal Diseases and Glomerulopathies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39534179
DOI: 10.3389/fneph.2024.1460146

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

C3 glomerulopathy: a kidney disease mediated by alternative pathway deregulationPMID 39534179Read ↗

C3 Glomerulopathy: A Current Perspective in an Evolving LandscapeSemantic proximity Read ↗

Complement inhibition in C3 glomerulopathy.Semantic proximity Read ↗

Acquired and genetic determinants of disease phenotype and therapeutic strategies in C3 glomerulopathy and immunoglobulin-associated MPGNSemantic proximity Read ↗

Defining the Complement Biomarker Profile of C3 GlomerulopathySemantic proximity Read ↗

Recent insights into C3 glomerulopathySemantic proximity Read ↗

Evolving complexity of complement-related diseasesSemantic proximity Read ↗

The role of the alternative pathway of complement activation in glomerular diseases.Semantic proximity Read ↗

C3 glomerulopathy: the genetic and clinical findings in dense deposit disease and C3 glomerulonephritis.Semantic proximity Read ↗

C3 glomerulopathy: what's in a name?Semantic proximity Read ↗

Diseases of complement dysregulation-an overview.Semantic proximity Read ↗

Treatment of C3 glomerulopathy with complement blockers.Semantic proximity Read ↗

C3 Glomerulopathy: Ten Years' Experience at Mayo Clinic.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.