Article
C3 glomerulonephritis and autoimmune disease: more than a fortuitous association?
Journal of nephrology - 1 Apr 2016
Alexander Mariam P, Fervenza Fernando C, De Vriese An S, Smith Richard J H, Nasr Samih H, Cornell Lynn D, Herrera Hernandez Loren P, Zhang Yuzhou, Sethi Sanjeev
Abstract excerpt
C3 glomerulonephritis (C3GN) results from genetic or acquired dysregulation of the alternative complement pathway. A subset of patients may have clinical and biochemical characteristics compatible with an autoimmune disorder. We studied a cohort of 85 patients with confirmed C3GN (2007-2014), of which ten patients (3 male, 7 female; mean age 38.5 years) had an associated autoimmune disorder. All patients had...
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