Article
C3 glomerulonephritis: clinicopathological findings, complement abnormalities, glomerular proteomic profile, treatment, and follow-up.
Kidney international - 1 Aug 2012
Sethi Sanjeev, Fervenza Fernando C, Zhang Yuzhou, Zand Ladan, Vrana Julie A, Nasr Samih H, Theis Jason D, Dogan Ahmet, Smith Richard J H
Abstract excerpt
C3 glomerulonephritis (C3GN) is a recently described disorder that typically results from abnormalities in the alternative pathway (AP) of complement. Here, we describe the clinical features, kidney biopsy findings, AP abnormalities, glomerular proteomic profile, and follow-up in 12 cases of C3GN. This disorder equally affected all ages, both genders, and typically presented with hematuria and proteinuria. In...
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