Article
Alzheimer's Disease Risk Genes and Lipid Regulators.
Journal of Alzheimer's disease : JAD - 23 Apr 2016
El Gaamouch Farida, Jing Ping, Xia Jiahong, Cai Dongming
Abstract excerpt
Brain lipid homeostasis plays an important role in Alzheimer's disease (AD) and other neurodegenerative disorders. Aggregation of amyloid-β peptide is one of the major events in AD. The complex interplay between lipids and amyloid-β accumulation has been intensively investigated. The proportions of lipid components including phospholipids, sphingolipids, and cholesterol are roughly similar across different brain...
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