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Article

Interferon lambda polymorphisms associate with body iron indices and hepatic expression of interferon-responsive long non-coding RNA in chronic hepatitis C.

Clinical and experimental medicine - 1 May 2017

Wróblewska Anna, Bernat Agnieszka, Woziwodzka Anna, Markiewicz Joanna, Romanowski Tomasz, Bielawski Krzysztof P, Smiatacz Tomasz, Sikorska Katarzyna

Abstract excerpt

Single nucleotide polymorphisms (SNPs) within DNA region containing interferon lambda 3 (IFNL3) and IFNL4 genes are prognostic factors of treatment response in chronic hepatitis C (CHC). Iron overload, frequently diagnosed in CHC, is associated with unfavorable disease course and a risk of carcinogenesis. Its etiology and relationship with the immune response in CHC are not fully explained. Our aim was to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27125837
DOI: 10.1007/s10238-016-0423-4
PMCID: PMC5403869

Genes

HAMP
IFNL3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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