Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms Related to Iron Homeostasis Associate with Liver Disease in Chronic Hepatitis C.

Viruses - 9 Aug 2023

Wróblewska Anna, Woziwodzka Anna, Rybicka Magda, Bielawski Krzysztof P, Sikorska Katarzyna

Abstract excerpt

Dysregulation of iron metabolism in chronic hepatitis C (CHC) is a significant risk factor for hepatic cirrhosis and cancer. We studied if known genetic variants related to iron homeostasis associate with liver disease progression in CHC. Retrospective analysis included 249 CHC patients qualified for antiviral therapy between 2004 and 2014. For all patients, nine SNPs within HFE, TFR2, HDAC2, HDAC3, HDAC5,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to CTLA-4 Antigen
Share to Hepatitis C, Chronic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homeostasis

Share to Liver Neoplasms

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 37632052
DOI: 10.3390/v15081710
PMCID: PMC10457817

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms Related to Iron Homeostasis Associate with Liver Disease in Chronic Hepatitis C.PMID 37632052Read ↗

Interferon lambda polymorphisms associate with body iron indices and hepatic expression of interferon-responsive long non-coding RNA in chronic hepatitis C.Semantic proximity Read ↗

Analysis of polymorphism and hepatic expression of duodenal cytochrome b in chronic hepatitis C.Semantic proximity Read ↗

Potentially functional genetic variants in ferroptosis-related CREB3 and GALNT14 genes predict survival of hepatitis B virus-related hepatocellular carcinoma.Semantic proximity Read ↗

Iron metabolism gene expression and prognostic features of hepatocellular carcinomaSemantic proximity Read ↗

Polymorphisms in histone deacetylases improve the predictive value of IL-28B for chronic hepatitis C therapy.Semantic proximity Read ↗

The effect of HFE gene mutation and iron overload on sustained virological response in Egyptian chronic hepatitis C patients treated with daclatasvir and sofosbuvir.Semantic proximity Read ↗

Iron and HFE or TfR1 mutations as comorbid factors for development and progression of chronic hepatitis C.Semantic proximity Read ↗

Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy.Semantic proximity Read ↗

Relative contribution of iron genes, dysmetabolism and hepatitis C virus (HCV) in the pathogenesis of altered iron regulation in HCV chronic hepatitis.Semantic proximity Read ↗

Genetic variants of IFIH1 and DHX58 affect the chronicity of hepatitis C in the Chinese Han population.Semantic proximity Read ↗

Expression of hepcidin and other iron-regulatory genes in human hepatocellular carcinoma and its clinical implicationsSemantic proximity Read ↗

Role of IFN-ks, IFN-ks related genes and the DEPDC5 gene in Hepatitis B virus-related liver disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.