Article
Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy.
Hepatology (Baltimore, Md.) - 1 Apr 2012
Lange Christian M, Kutalik Zoltan, Morikawa Kenichi, Bibert Stéphanie, Cerny Andreas, Dollenmaier Günter, Dufour Jean-François, Gerlach Tilman J, Heim Markus H, Malinverni Raffaele, Müllhaupt Beat, Negro Francesco, Moradpour Darius, Bochud Pierre-Yves
Abstract excerpt
UNLABELLED: Elevated serum ferritin levels may reflect a systemic inflammatory state as well as increased iron storage, both of which may contribute to an unfavorable outcome of chronic hepatitis C (CHC). We therefore performed a comprehensive analysis of the role of serum ferritin and its genetic determinants in the pathogenesis and treatment of CHC. To this end, serum ferritin levels at baseline of therapy with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.