Article
Association of IFNL3 and IFNL4 polymorphisms with hepatitis C virus infection in a population from southeastern Brazil.
Archives of virology - 1 Jun 2016
de Seixas Santos Nastri Ana Catharina, de Mello Malta Fernanda, Diniz Márcio Augusto, Yoshino Alessandra, Abe-Sandes Kiyoko, Dos Santos Sidney Emanuel Batista, de Castro Lyra André, Carrilho Flair José, Pinho João Renato Rebello
Abstract excerpt
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease and associated complications such as liver cirrhosis and hepatocellular carcinoma (HCC). Viral and host factors are known to be predictors for antiviral therapy. Host factors that are predictors of sustained viral response (SVR) were discovered by genome-wide association studies (GWAS), including single-nucleotide polymorphisms (SNPs) in...
Topics
- Adult
- Antiviral Agents
- Brazil
- Female
- Genome-Wide Association Study
- Haplotypes
- Hepatitis C, Chronic
- Host-Pathogen Interactions
- Humans
- Interferon-alpha