Article
Gene-disease association with human IFNL locus polymorphisms extends beyond hepatitis C virus infections.
Genes and immunity - 1 Jul 2016
Chinnaswamy S
Abstract excerpt
Interferon (IFN) lambda (IFN-λ or type III IFN) gene polymorphisms were discovered in the year 2009 to have a strong association with spontaneous and treatment-induced clearance of hepatitis C virus (HCV) infection in human hosts. This landmark discovery also brought renewed interest in type III IFN biology. After more than half a decade since this discovery, we now have reports that show that genetic association...
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