Article
Association of genetic variants with tumor HPV16 status and survival in squamous cell carcinoma of the oropharynx.
Oral oncology - 1 May 2016
Feng Yun, Li Yuncheng, Zhang Yang, Zheng Hongliang, Li Guojun
Abstract excerpt
OBJECTIVES: Genetic polymorphisms of genes in cell cycle, apoptosis, and inflammation/immune response pathways may control the mechanisms of HPV clearance and HPV escape of immune surveillance and thus may affect both tumor HPV16 status and possibly related outcomes of squamous cell carcinoma of the oropharynx (SCCOP) patients. MATERIALS AND METHODS: We determined tumor HPV16 status and genotyped selected...
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