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Article

Association of tumor necrosis factor-alpha promoter variants with risk of HPV-associated oral squamous cell carcinoma.

Molecular cancer - 19 Jul 2013

Jin Lei, Sturgis Erich M, Zhang Yang, Huang Zhigang, Song Xicheng, Li Chao, Wei Qingyi, Li Guojun

Abstract excerpt

BACKGROUND: Tumor necrosis factor alpha (TNF-α) plays an important role in inflammation, immunity, and defense against infection and clearance of human papillomavirus (HPV). Thus, genetic variants may modulate individual susceptibility to HPV-associated oral squamous cell carcinoma (OSCC). METHODS: In this study we genotyped four common single nucleotide polymorphisms (SNPs) in the TNF-α promoter [...

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Identifiers

PMID: 23870134
DOI: 10.1186/1476-4598-12-80
PMCID: PMC3725173

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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