Article
Association of TGF-beta1 genetic variants with HPV16-positive oropharyngeal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2010
Guan Xiaoxiang, Sturgis Erich M, Lei Dapeng, Liu Zhensheng, Dahlstrom Kristina R, Wei Qingyi, Li Guojun
Abstract excerpt
PURPOSE: Transforming growth factor-beta1 (TGF-beta1) plays an important role in inflammation and immune responses, which control the human papillomavirus (HPV) clearance and escape of immune surveillance, and may contribute to genetic susceptibility to HPV16 infection. EXPERIMENTAL DESIGN: In th...
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