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Article

Interleukin-10 promoter variants predict HPV-positive tumors and survival of squamous cell carcinoma of the oropharynx.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jun 2013

Jin Lei, Sturgis Erich M, Cao Xiaolin, Song Xicheng, Salahuddin Taufiq, Wei Qingyi, Li Guojun

Abstract excerpt

Interleukin-10 (IL-10) plays an important role in a host's defense against human papillomavirus (HPV) infection. IL-10 promoter variants may affect its expression level or functional efficiency and, subsequently, susceptibility to and survival of HPV16-associated squamous cell carcinoma of oropharynx (SCCOP). We determined tumor HPV16 DNA and genotyped three IL-10 promoter polymorphisms in 309 incident patients...

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Share to Carcinoma, Squamous Cell
Share to Human papillomavirus 16

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Oropharyngeal Neoplasms

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Share to Promoter Regions, Genetic

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Source

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Identifiers

PMID: 23430974
DOI: 10.1096/fj.12-226803
PMCID: PMC3659362

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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