Article
Association of AKR1C3 Polymorphisms with Bladder Cancer.
Urology journal - 16 Apr 2016
Tiryakioglu N Ozan, Tunali Nagehan Ersoy
Abstract excerpt
PURPOSE: Polymorphisms in the genes coding for the carcinogen metabolizing enzymes may affect enzyme activities and alter the activation and detoxification rates of the carcinogens. AKR1C3 is one of the very polymorphic xenobiotic metabolizing enzymes involved in the bioactivation process. Here we aimed to investigate the association of two single nucleotide polymorphisms in AKR1C3, rs12529 (c.15C > G) and...
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