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Polymorphisms in drug-metabolizing genes and urinary bladder cancer susceptibility and prognosis: Possible impacts and future management.

Gene - 20 May 2024

Silva Isabely Mayara da, Vacario Beatriz Geovana Leite, Okuyama Nádia Calvo Martins, Barcelos Gustavo Rafael Mazzaron, Fuganti Paulo Emílio, Guembarovski Roberta Losi, Cólus Ilce Mara de Syllos, Serpeloni Juliana Mara

Abstract excerpt

Epidemiological studies have shown the association of genetic variants with risks of occupational and environmentally induced cancers, including bladder (BC). The current review summarizes the effects of variants in genes encoding phase I and II enzymes in well-designed studies to highlight their contribution to BC susceptibility and prognosis. Polymorphisms in genes codifying drug-metabolizing proteins are of...

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Identifiers

PMID: 38350514
DOI: 10.1016/j.gene.2024.148252

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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