Article
Association between CYP1A2 gene variants -163 C/A (rs762551) and -3860 G/A (rs2069514) and bladder cancer susceptibility.
BMC cancer - 22 Jul 2024
Iqbal Muhammad Sarfaraz, Sardar Nimra, Peng Kaoqing, Almutairi Layla A, Duan Xialo, Tanvir Fouzia, Attia Kotb A, Zeng Gouhua, Gu Di
Abstract excerpt
BACKGROUND: Bladder cancer (BLCA) poses a significant global health challenge due to its high incidence, poor prognosis, and limited treatment options. AIMS AND OBJECTIVES: This study aims to investigate the association between two specific polymorphisms, CYP1A2-163 C/A and CYP1A2-3860G/A, within the Cytochrome P450 1A2 (CYP1A2) gene and susceptibility to BLCA. METHODS: The study employed a case-control design,...
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