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Article

Fimbrin phosphorylation by metaphase Cdk1 regulates actin cable dynamics in budding yeast.

Nature communications - 12 Apr 2016

Miao Yansong, Han Xuemei, Zheng Liangzhen, Xie Ying, Mu Yuguang, Yates John R, Drubin David G

Abstract excerpt

Actin cables, composed of actin filament bundles nucleated by formins, mediate intracellular transport for cell polarity establishment and maintenance. We previously observed that metaphase cells preferentially promote actin cable assembly through cyclin-dependent kinase 1 (Cdk1) activity. However, the relevant metaphase Cdk1 targets were not known. Here we show that the highly conserved actin filament...

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Identifiers

PMID: 27068241
DOI: 10.1038/ncomms11265
PMCID: PMC4832064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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