Article
FAM190A deficiency creates a cell division defect.
The American journal of pathology - 1 Jul 2013
Patel Kalpesh, Scrimieri Francesca, Ghosh Soma, Zhong Jun, Kim Min-Sik, Ren Yunzhao R, Morgan Richard A, Iacobuzio-Donahue Christine A, Pandey Akhilesh, Kern Scott E
Abstract excerpt
Like the p16, SMAD4, and RB1 genes, FAM190A (alias CCSER1) lies at a consensus site of homogeneous genomic deletions in human cancer. FAM190A transcripts in 40% of cancers also contain in-frame deletions of evolutionarily conserved exons. Its gene function was unknown. We found an internal deleti...
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