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Article

Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis.

The Journal of cell biology - 7 Nov 2005

Yamaguchi Tomoya, Goto Hidemasa, Yokoyama Tomoya, Silljé Herman, Hanisch Anja, Uldschmid Andreas, Takai Yasushi, Oguri Takashi, Nigg Erich A, Inagaki Masaki

Abstract excerpt

Several kinases phosphorylate vimentin, the most common intermediate filament protein, in mitosis. Aurora-B and Rho-kinase regulate vimentin filament separation through the cleavage furrow-specific vimentin phosphorylation. Cdk1 also phosphorylates vimentin from prometaphase to metaphase, but its significance has remained unknown. Here we demonstrated a direct interaction between Plk1 and vimentin-Ser55...

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Identifiers

PMID: 16260496
DOI: 10.1083/jcb.200504091
PMCID: PMC2171270

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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